UK Validation of the Automated "AcceXible" Speech Analysis Software

• Conditions: Mild Cognitive Impairment and Dementia
• Interventions: Device: Accexible

• Registration Number: NCT05534958
• Lead Sponsor: Accexible

Brief Summary

Dementia, especially dementia caused by Alzheimer's disease, is considered one of the most severe health problems of our time. It is currently known that the disease begins many years before clinical symptoms appear. The sooner the patient is diagnosed, the sooner the patient will be in a position to prevent further deterioration.

A recent orientation is the analysis of language in relation to the description of images with a high and varied semantic and emotional content. It can be studied that changes in the description of an image check if these changes are associated with the evolution of a person with probable impairment both in memory and cognitive as well as emotional, psychiatric, behavioral and even in their interaction with environmental factors especially those associated with socialization and loneliness.

The present study has the objective of validating a digital method for detection and follow-up of patients with mild cognitive impairment (MCI) or dementia in a memory clinic setting.

Detailed Description

Not available

Study Timeline

• Status Verified: 2022-08
• Study Start: 2022-08-01
• Study First Submitted: 2022-09-07
• Study First Submitted QC: 2022-09-07
• Last Update Submitted: 2022-09-07
• Study First Posted: 2022-09-10
• Last Update Posted: 2022-09-10
• Primary Completion: 2023-12-31
• Study Completion: 2023-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 248

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Early Dementia	Accexible	-
Healthy	Accexible	-
Mild Cognitive Impairment	Accexible	-

Primary Outcome Measures

Name	Time	Method
Diagnostic performance of Accexible's digital screening battery	An average of 1 year	Measure the odds that a patient has MCI or dementia measured by vocal biomarkers

Secondary Outcome Measures

Name	Time	Method
Correlation of Accexible's test battery with the ACE III	An average of 1 year	Comparison of Accexible's test battery with ACE III diagnostic predictive value at various cut-off points (e.g. 82 and 88 for ACE III)

Trial Locations

Locations (1)

Cornwall Partnership NHS Foundation Trust; 🇬🇧 Cornwell, United Kingdom