The Comparison of the effects of metformin and insulin in the treatment of hyperglycemia
Not Applicable
- Conditions
- Condition 1: Hyperglycemia after coronary artery bypass surgery. Condition 2: Hyperglycaemia.Other functional disturbances following cardiac surgeryHyperglycaemia, unspecified
- Registration Number
- IRCT2015072311399N2
- Lead Sponsor
- Vice chancellor for research, Semnan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Glycosylated hemoglobin less than 7%; Blood glucose above 150 mg/dl; Elective coronary artery bypass surgery; Age between 35 to 75 years old; The use of cardiopulmonary bypass; Hemodynamically stable(BP>70 mmHg and PR between 50 and 110).
Exclusion criteria: History of diabetes; GFR less than 60%; life-threatening arrhythmias; Prolonged intubation; The use of inotropic agents for hemodynamic stability; Potassium level higher than 5.5 or less than 3.5 on admission in ICU; Metabolic acidosis lower than 7.25 or lactate level higher than 4.5 mg/dl or BE less than 6 mmo/L; Pao 2 less than 60 mm Hg; The patient is NPO
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood Suger. Timepoint: Up to 6 hours after surgery each time and then every 6 hours. Method of measurement: Glucometer device.
- Secondary Outcome Measures
Name Time Method actat. Timepoint: Q 12 Hr. Method of measurement: Using of ABG machine.