Comparison of two local anesthetics for spinal anesthesia in caesarean section

Not yet recruiting

• Conditions: Sequelae of complication of pregnancy, childbirth, and the puerperium,

• Registration Number: CTRI/2024/01/061890
• Lead Sponsor: Dr Shivakumar G

Brief Summary

The study aims in comparing the anaesthetic profile and effects of intrathecal hyperbaric ropivacaine 0.75% and hyperbaric bupivacaine 0.5% in spinal anaesthesia for elective caesarean section in a group of 80 people by using the following parameters: Primary objectives: 1. Onset and duration of sensory blockade (T6 dermatome). 2. Onset and duration of motor blockade. Secondary objectives: 1.Intraoperative hemodynamic parameters. 2.Duration of analgesia (until first dose of analgesia demand). 3.Adverse effects.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-01-02
• Last Update Posted: 2024-01-19

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 80

Inclusion Criteria

• Patients posted for elective caesarean section surgeries.
• Age group 18 to 40 years.
• Patients with height 150cm-180cm and weight 40kg-80kg.
• Patients with American Society of Anaesthesiologists-Physical status (ASA-PS) grade I and II.
• Patients willing to give informed consent to participate in the study.

Exclusion Criteria

• Patients with cardiovascular diseases or pregnancy induced hypertension and gestational diabetes mellitus.
• Patients having increased intracranial tension, severe hypovolemia, history of bleeding diathesis and local infection.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparing the onset and duration of sensory and motor blockade.	24 hours

Secondary Outcome Measures

Name	Time	Method
To compare the anaesthetic profile and effects of intrathecal hyperbaric ropivacaine 0.75% and hyperbaric bupivacaine 0.5% in spinal anaesthesia for elective caesarean section by using the following parameters:	1.Intraoperative hemodynamic parameters.

Trial Locations

Locations (1)

MANDYA INSTITUTE OF MEDICAL SCIENCES; 🇮🇳 Mandya, KARNATAKA, India

MANDYA INSTITUTE OF MEDICAL SCIENCES

🇮🇳Mandya, KARNATAKA, India

Dr ASWIN M ULLAS

Principal investigator

9400864833

aswinmullas@gmail.com