Prediction of a space-occupying ischaemic stroke by ultrasound in patients with a large vessel occlusion and comparison with CT/MRI

Recruiting

Conditions: I63.0
I63.1
I63.2
I63.8
I63.9
I63.3
I63.4
I63.5
I63.6
Cerebral infarction due to thrombosis of precerebral arteries

Registration Number: DRKS00023313

Lead Sponsor: Klinik und Poliklinik für Neurologie, Universitätsklinikum Leipzig

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 77

Inclusion Criteria

1. Age over 18 years.
2. Initial occlusion of the internal carotid artery or the proximal middle cerebral artery (M1- or the dominating M2-segment).
3. An ASPECTS of =8 points in the initial native cerebral CT OR a futile mechanical thrombectomy.
4. The first ultrasound examination can be done with 12 hours after symptom onset.
5. Aggreement to participate in this study by either the patient (written or under witness) or by a physician with later confirmation by the patient itself or a legal representive).

Exclusion Criteria

1. Injury of the eyeball or the temporal bone.
2. Pregnant or breast-feeding patients.

Study & Design

Study Type: observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intermethodagreement for the assessment of the midline shift via ultrasound and cerebral CT /MRI

Secondary Outcome Measures

Name	Time	Method
1. Dynamics of the sonographic midline shift, of the opticus nerve sheath diameter, and the pupillary diameter as predictor for the development of a space occupying cerebral infarction.<br><br>2. Correct identification of those patients by ultrasound that will develop a space occupying cerebral infarction.<br><br>3. Assessment of the interrater aggreement between the initial ultrasound examiner and the central assessor who will repeat all measurements on short videorecordings of the ultrasound examination.