Open randomized controlled trial to evaluate efficacy of clindamycin in the pulmonary Mycobacterium avium complex disease
Not Applicable
Recruiting
- Conditions
- Pulmonary Mycobacterium avium complex disease
- Registration Number
- JPRN-UMIN000016615
- Lead Sponsor
- Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
1. Patients receiving other antibiotic treatments. 2. Contraindication for clindamycin, clarithromycin, rifampicin, ethambutol administration 3. Patients deemed ineligible by the attending physicians for various reasons. 4. Patients with serious heart disorders
Study & Design
- Study Type
- Interventional,observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Findings of chest high resolution computed tomography before and after clindamycin treatment
- Secondary Outcome Measures
Name Time Method 1. Symptoms, laboratory data, spirometry 2. Bacteriological efficacy: sputum culture, and bacterial floral analysis findings of bronchoalveolar lavage fluid culture 3. Safety and adverse effects of clindamycin treatment