NCT07268235已完成不适用
Timing of Oocyte Retrieval and Micro Testicular Sperm Extraction: Does it Make a Difference? A Single-center Retrospective Cohort
Clinique Ovo1 个研究点 分布在 1 个国家目标入组 129 人开始时间: 2025年11月15日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 129
- 试验地点
- 1
- 主要终点
- Number of live births following ICSI with micro-TESE either 24 or 48 hours prior to oocyte retrieval
研究概览
简要总结
This is a retrospective study to assess outcomes of micro-TESE performed 24 or 48 hours before oocyte retrieval and ICSI.
详细描述
This retrospective study evaluates patients undergoing ICSI following micro-TESE. Participants are assigned to two groups based on the interval between sperm extraction and oocyte retrieval (24 vs. 48 hours). Clinical and embryological outcomes from the first embryo transfer will be assessed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Men who underwent a micro-TESE at the OVO clinic from June 2015 to January
- •Patients with non-obstructive azoospermia (NOA), (absence of spermatozoa in multiple semen analyses)
- •Patients with cryptozoospermia, (presence of a small number of spermatozoa detectable only after semen centrifugation)
- •Patients with oligoasthenoteratozoospermia (OAT), (sperm concentration of less than 15 million/mL, reduced motility and abnormal morphology)
排除标准
- •Patients who did not have any sperm noted following micro-TESE
- •Use of donor sperm or oocytes
- •Frozen sperm or oocytes
- •Same day oocyte retrieval and sperm extraction
- •Reversible cause of cryptozoospermia (i.e presence of a varicocele, febrile illness, or recent toxin exposure) Partial genital tract obstruction (i.e post-vaso-vasostomy, post-vasoepididymostomy, and low volume cryptozoospermia with ejaculatory duct obstruction)
结局指标
主要结局
Number of live births following ICSI with micro-TESE either 24 or 48 hours prior to oocyte retrieval
时间窗: For IVF performed from June 2015 to January 2025
次要结局
- Percentage of fertilized oocytes with two pronuclei (2PN)(For IVF performed from June 2015 to January 2025)
- Percentage of usable blastocyst (defined as frozen and transferred blastocysts)(For IVF performed from June 2015 to January 2025)
- Pregnancy rate based on positive β-hCG(For IVF performed from June 2015 to January 2025)
研究者
研究点 (1)
Loading locations...
相似试验
撤回
4 期
Ovarian Stimulation: Inositol and MelatoninInfertilityNCT01267604AGUNCO Obstetrics and Gynecology Centre
进行中（未招募）
不适用
The Effect of Follicular Flushing on Oocyte Retrieval Rate and Embryo QualityInfertilityNCT05584436Akdeniz University852
Unknown
4 期
Surgical Ovarian Drilling Versus Hormonal Treatment for Infertility Associated to PolyCystic Ovaries Syndrome (PCOS)Polycystic Ovary SyndromeNCT00378729Assistance Publique - Hôpitaux de Paris252
尚未招募
不适用
Study of Endometrial Immune and Microbiological Modifications in Cases of Recurrent Implantation Failure and/or Recurrent Pregnancy LossEndometriosisEndometritisNCT07265505Assistance Publique - Hôpitaux de Paris100
已完成
4 期
米索前列醇阴道片对足月妊娠妇女促宫颈成熟和引产有效性及安全性的多中心临床试验CTR202309361,500