JPRN-UMIN000014595已完成4 期
A Randomized, Double-Blind, Placebo-Controlled, Crossover Study of NSAID for the control of Acid-Induced Heartburn Symptom in Healthy Volunteers - Effect of NSAID on heartburn
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 12
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 45years-old（—）
- 性别
- Male
入选标准
- 未提供
排除标准
- •1. Subjects who undergo upper gastrointestinal endoscopy and are found to have significant organic diseases (e.g., esophagitis, Barrett's esophagus, hiatus hernia, active peptic ulcer disease, and esophageal/gastric cancer) 2. Subjects with medical history of asthma or allergy to NSAIDs 3. Subjects with history of peptic ulcer or GERD or of upper GI tract surgery 4. Subjects with significant cardiovascular, kidney, liver, neurotic, or psychological disorders 5. Subjects with FSSG total score of >8 6. Subjects taking medications that may affect prostaglandin generation, including NSAIDs, COX-2 inhibitors, or prostaglandin-containing medications 7. Individuals judged by investigators as ineligible for study enrollment.
研究者
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