Comparison of Lidocaine Spray and Paracervical Block Application for Pain Relief During First-trimester Surgical Abortion: a Randomized, Double-blind, Placebo-controlled Trial
Overview
- Phase
- Not Applicable
- Intervention
- Paracervical block + lidocaine spray
- Conditions
- Pain Score
- Sponsor
- Kayseri Education and Research Hospital
- Enrollment
- 108
- Locations
- 1
- Primary Endpoint
- Pain Scores on the Visual Analog Scale
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
Objective: The investigators sought to investigate the analgesic efficiency of lidocaine spray, paracervical block (PCB) with lidocaine and PCB with lidocaine plus lidocaine spray combination in patients undergoing first-trimester surgical abortion.
Methods: A randomized, double-blind, placebo-controlled clinical trial was conducted on 108 women with the request of pregnancy termination.The subjects were randomly assigned into four groups: PCB (n=27), lidocaine spray (n=27), PCB plus lidocaine spray (n=27) and placebo(n=27).Intraoperative and postoperative pain scores were measured with a standard Visual Analog Scale (VAS).
Investigators
Gökhan Açmaz
MD
Kayseri Education and Research Hospital
Eligibility Criteria
Inclusion Criteria
- •Age \>18 years Single Pregnancy \<7 weeks of gestation
Exclusion Criteria
- •Incomplete abortion Early pregnancy failure Acute cervicitis Untreated pelvic inflammatory disease Cervical stenosis
Arms & Interventions
Paracervical block plus lidocaine spray
Lidocaine injection+Lidocaine spray received PCB with 2 ampoules of lidocaine solution plus 2 pumps (20 mg=2 pumps) of 10% lidocaine spray
Intervention: Paracervical block + lidocaine spray
paracervical block plus isotonic saline spray
2 ampoules of lidocaine solution (20 mg Lidocaine HCl+0.0125 mg epinephrine/ml) plus isotonic spray
Intervention: Paracervical block
only lidocaine spray
paracervical block with saline solution plus 10% lidocaine spray
Intervention: Lidocaine spray
Outcomes
Primary Outcomes
Pain Scores on the Visual Analog Scale
Time Frame: Three months