Comparison of Functionality, Physical Activity, Cardiac and Respiratory Parameters Between Patients With Mood Disorders and Healthy Controls
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Mood Disorders
- Sponsor
- Mustafa Kemal University
- Enrollment
- 65
- Locations
- 1
- Primary Endpoint
- 3 minute step test (Assessment of exercise capacity)
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
The importance of cardiorespiratory impact in mental diseases is generally emphasized in studies, but it is noteworthy that cardiorespiratory affects in mood disorders have not been sufficiently investigated. This study aims to compare individuals with mood disorders and healthy people in terms of exercise capacity, functionality, respiratory muscle strength, respiratory functions, dyspnea and physical activity level.
Detailed Description
The cross-sectional study was carried out with 30 patients with diagnosis of mood disorder who applied to the Hatay Mustafa Kemal University Research and Practice Hospital, Mental Health and Diseases clinic, and 35 healthy individuals whose age, gender were matched. Clinical characteristics, exercise capacity (6-minute walking test, 6MWT; 3-minute Step test, 3MST), functionality (vertical jump test, functional reach test), respiratory parameters (Respiratory muscle strength, pulmonary function test), dyspnea (Modified Medical Research Council, MMRC scale), physical activity level (short form international physical activity questionnaire, IPAQ) was evaluated.
Investigators
Irem Hüzmeli
assistant professor
Mustafa Kemal University
Eligibility Criteria
Inclusion Criteria
- •Healthy volunteers who had undergone a general physical examination in the past 6 month
- •reported being free of significant cardiovascular, respiratory, neuromuscular, and endocrine disorders that preclude safe participation
Exclusion Criteria
- •Individuals with significant cardiovascular, neuromuscular and endocrine disorders,
- •pregnant women,
- •people under 18 years old
- •disabled individuals.
Outcomes
Primary Outcomes
3 minute step test (Assessment of exercise capacity)
Time Frame: Baseline
3 minute step test, In this test, the person ascends and descends the 30.5 cm step with the rhythm of the metronome set at 96 beats/min for 3 minutes.
Six minute walking test (Evaluation of exercise capacity)
Time Frame: Baseline
Six minute walking test, The patients were allowed to rest for at least 30 minutes pre-starting the test, which was performed according to ATS criteria. The participants were asked to walk as fast as they can without running in a 30-meter straight corridor for 6 minutes at their own walking pace
Secondary Outcomes
- Physical activity(Baseline)
- forced expiratory volume in the first second (FEV1) (Pulmonary function)(Baseline)
- Vertical jump test (Functionality 1)(in a time through the study completion, an average of 5 minutes)
- The Functional Reaching Test (Functionality 2)(Baseline)
- Forced vital capacity (FVC) (Pulmonary function)(Baseline)
- ratio of forced expiratory volume in the first second to forced vital capacity (FEV1/FVC)(Baseline)
- peak expiratory flow rate (PEF)(Baseline)
- forced mid-expiratory flow rate (FEF25-75%)(Baseline)
- Respiratory muscle strenght(Baseline)