Intraocular Pressure Reduction With the Bimatoprost/Timolol Fixed Combination

Phase 4

Completed

• Conditions: Glaucoma; Ocular Hypertension

• Registration Number: NCT00941096
• Lead Sponsor: Larissa University Hospital

Brief Summary

The purpose of this study is to examine the ocular hypotensive effect of Bimatoprost and the potential additional effect of the Bimatoprost/Timolol fixed combination in eyes with ocular hypertension, primary open angle glaucoma or exfoliation glaucoma.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-07
• Study First Submitted: 2009-07-16
• Study First Submitted QC: 2009-07-16
• Study First Posted: 2009-07-17
• Status Verified: 2010-11
• Primary Completion: 2010-11
• Study Completion: 2010-11
• Last Update Submitted: 2010-11-29
• Last Update Posted: 2010-11-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Primary open angle glaucoma
• Exfoliation glaucoma
• Ocular hypertension

Exclusion Criteria

• Younger than 18 years old
• Inability to understand and/or follow study requirements
• Women of childbearing potential not using reliable birth control, pregnant or lactating women
• History of chronic obstructive pulmonary disease, heart failure, 2nd or 3rd AV block
• Anticipated modification of treatment for systemic hypertension during the study period
• History of ocular herpes, corneal scarring, conventional or laser surgery or macular pathology
• History of allergy, poor tolerability or poor response to study medication
• Best corrected visual acuity less than 0.4
• Significant visual field defect (MD<15.0 dB)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Mean diurnal intraocular pressure	Five weeks on each medication

Trial Locations

Locations (1)

University Eye Clinic; 🇬🇷 Larissa, Thessaly, Greece