Tailored interventions to improve adherence to medication in elderly patients with Parkinson’s disease: a randomized controlled trial

Not Applicable

Completed

• Conditions: on-Adherence; G20; Parkinson disease

• Registration Number: DRKS00023655
• Lead Sponsor: Department of Neurology, Jena University Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-02-24
• Study Completion: 2023-12-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 132

Inclusion Criteria

The patient is clinically diagnosed with Parkinson‘s disease according to the MDS-criteria
- Montreal cognitive assessment (MoCA) = 19/30 points
- Patient manages his medication independently
- Presence of self-reported non-adherence according to the German Stendal Adherence with Medication Score (SAMS > 1)
- Informed consent is obtained from the participant

Exclusion Criteria

- Acute psychotic symptoms, delirium
- Montral cognitive assessment (MoCA) < 19/30
- Patient is not actively involved in drug management (e.g., bedridden in nursing home)
- Inability to provide informed consent

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary endpoint in this study is motor function assessed with the combined MDS-UPDRS II and MDS-UPDRS III (revised Unified Parkinson's Disease Rating) after 6 months in the control vs. AdhCare arm (Intent-To-Treat).

Secondary Outcome Measures

Name	Time	Method
Self-reported adherence (SAMS), Medication adherence scores, Number of Primary Care Visits. We will also qualitatively evaluate the perception of intervention and barriers and facilitators for the implementation. Will be assessed after 3 and 6 month.