Prevalence of Thyroid Disorders in Patients With Immune Thrombocytopenic Purpura and Its Impact on Treatment

Not yet recruiting

• Conditions: Immune Thrombocytopenic Purpura; Thyroid Disorders
• Interventions: Diagnostic Test: Search for thyroid disorders; Diagnostic Test: Laboratory test; Drug: Steroid and eltrombopage

• Registration Number: NCT07059910
• Lead Sponsor: Assiut University

Brief Summary

Prevalence of thyroid disorders in patients with immune thrombocytopenic purpura and its impact on treatment

Detailed Description

We investigate patients with ITP for screening of thyroid disorders and how to deal with it and effect of this on the ttt

Study Timeline

• Study First Submitted: 2025-06-10
• Status Verified: 2025-07
• Study Start: 2025-07-01
• Study First Submitted QC: 2025-07-01
• Study First Posted: 2025-07-11
• Last Update Submitted: 2025-07-13
• Last Update Posted: 2025-07-17
• Primary Completion: 2026-05-31
• Study Completion: 2026-08-15

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• ITP patients will be classified as newly diagnosed, persistent and chronic based on duration less than 3 months, 3-12 months, and more than 12 months respectively.

  • refractory ITP patients.

Exclusion Criteria

• patients with history of thyroidectomy

  • patients with history of drug induced ITP
  • patients with history of HCV, HBV and HIV infection.
  • Patients who refuse to contribute in this study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients known ITP	Search for thyroid disorders	Patients known ITP either newly diagnosed, chronic, refractory Age 18 yrs and above Patients with thyrodiectomy will not be in our study
Patients known ITP	Laboratory test	Patients known ITP either newly diagnosed, chronic, refractory Age 18 yrs and above Patients with thyrodiectomy will not be in our study
Patients known ITP	Steroid and eltrombopage	Patients known ITP either newly diagnosed, chronic, refractory Age 18 yrs and above Patients with thyrodiectomy will not be in our study

Primary Outcome Measures

Name	Time	Method
Assess the frequency of thyroid disorders in patients with IT	Assess the frequency of thyroid disorders in patients with IT	Screening of thyroid disorders in patients with ITP
Evaluate the treatment of thyroid disorders in improvement in platelets count.	Evaluate the treatment of thyroid disorders in improvement in platelets count.	Evaluate if patients have managed according to thyroid disorders, will this affect in their response to ITP management