Establishing First Trimester Markers for the Identification of High Risk Twin

• Conditions: Small for Gestational Age (Disorder); Pre-Eclampsia

• Registration Number: NCT02031393
• Lead Sponsor: Assaf-Harofeh Medical Center

Brief Summary

The purpose of this study is to determine whether we can establish different markers suc as mean arterial pressure , flow in the uterine arteries, biochemical markers in maternal blood and more un the first trimester, in order to screen for twin pregnancies that are more likely to develop adverse pregnancy outcome: early delivery, pre eclampsia or small fetuses.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-09
• Status Verified: 2013-12
• Primary Completion: 2014-01
• Study First Submitted: 2014-01-08
• Study First Submitted QC: 2014-01-08
• Study First Posted: 2014-01-09
• Last Update Submitted: 2014-01-30
• Last Update Posted: 2014-01-31
• Study Completion: 2014-07

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 300

Inclusion Criteria

• pregnant women from 11 -14 weeks of gestation

Exclusion Criteria

• nuchal thickness above 3 mm,
• Chronic hypertension,
• thrombophilia,
• Diabetes

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The development of preeclampsia	after delivery	the women will be approached after birth to asses whether they developed preeclampsia or pregnancy induced hypertension

Secondary Outcome Measures

Name	Time	Method
intra uterine growth restriction	after delivery

Trial Locations

Locations (1)

Assaf Harofe obstetric department; 🇮🇱 Be'er Ya'aqov, Zrifin, Israel