Medical Management of Second Trimester Missed Miscarriage using a combination of Mifepristine-misoprostol versus Misoprostol alone
Not Applicable
Recruiting
- Conditions
- Missed miscarriage
- Registration Number
- PACTR202311776445720
- Lead Sponsor
- Rabiatu Musa Ahmed
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 72
Inclusion Criteria
Patients diagnosed with a missed miscarriage by pelvic ultrasound scan in the second trimester of pregnancy
Patients who give informed consent to medical management of missed miscarriage in second trimester.
Exclusion Criteria
Patients with known allergy to mifepristone or misoprostol
Patients with coagulation disorders
Patients with a previous Caesarean delivery/myomectomy
Life threatening bleeding,
Contraindications to mifepristone or misoprostol,
Patients who do not give consent
Patients who opt for alternative means of miscarriage management
Patients with multiple gestation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome measures include; treatment success as defined by complete expulsion of the products of conception and no need for any additional medical and/or surgical intervention.<br>
- Secondary Outcome Measures
Name Time Method Secondary outcome measures include; intervention-complete expulsion interval, use of additional doses of misoprostol to effect expulsion, surgical intervention to complete miscarriage, use of oxytocin to aid expulsion of products of conception, side-effects of the medications used and complications of the miscarriage process such as excessive hemorrhage, retained placenta, etc.<br>