MedPath

Effect of Dr Dixit Lifestyle on HbA1c level

Phase 3
Not yet recruiting
Conditions
Overweight, (2) ICD-10 Condition: E119||Type 2 diabetes mellitus without complications,
Registration Number
CTRI/2022/03/041035
Lead Sponsor
Chitale group Bhilawadi
Brief Summary

Diabetes is a widespread metabolic condition with an estimated 10% of the population in India being prediabetic and 10% being diabetic. The prevalence is on rise. The latest statement issued by American Diabetes Association regarding standards of medical care in diabetes and a consensus statement by the American College of Endocrinology and the American Association of Clinical Endocrinologists recommend lifestyle intervention as the preferred treatment option for prediabetes and newly diagnosed diabetes up to 3 months, as it has been shown to be safe and highly effective, reducing the progression to type 2 diabetes by more than 40%. Unfortunately the lifestyle suggested in present era which includes multiple small meals and exercise has failed to show its results. It is common to see that in almost all patients of type 2 diabetes, the doses and number of medicines for diabetes keep on increasing during the progress of disease. 

The principal investigator of this study has initiated "World free of obesity and diabetes" campaign in 2013. In this campaign 2 Only Meals and Exercise (2-OMEX) lifestyle popularly known as  Dr Dixit Lifestyle is advised to participants. In this lifestyle the person is supposed to eat only two meals when he/she is really hungry. In between two meals the person can take water, thin home made buttermilk and black tea (all these without adding sugar/jaggery/honey/sugar substitute). With this the person is supposed to walk for 4.5 Km at a stretch everyday. Research papers published so far indicate that this lifestyle causes average weight loss to the tune of 6.8 Kg in six months. It also causes reduction in fasting insulin level. It can also cause reversal of prediabetes status. Case report of diabetes remission is also published.

The hypothesis is that by reducing eating frequency the insulin level in body decreases. This makes body to use fats for energy. It increases insulin sensitivity and reverses ill effects of insulin resistance. The present study is conducted with the aim to see effect of this lifestyle on HbA1c levels in prediabetes and diabetes and also to see the remission in diabetes.

If the results are encouraging then we will have a lifestyle that is free of cost, does not require a doctor/expert, does not require you to buy any machine or nutritional supplements and most importantly one can follow it happily for life time!

Detailed Description

Not available

Recruitment & Eligibility

Status
Not Yet Recruiting
Sex
Male
Target Recruitment
147
Inclusion Criteria

Prediabetics with HbA1c from 5.7 to 6.4; People diagnosed with type 2 diabetes without any complications; may or may not be on anti diabetic medication; should be able to self report regarding meals and exercise.

Exclusion Criteria

Participants with diagnosed cardiovascular disease, nephropathy, retinopathy, neuropathy or diabetic foot; those unable to do exercise; those who do not give consent.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Reduction in HbA1c by 1gm% in diabetics and 0.5 gm% in prediabeticsEvery month for 12 months in diabetics and every three months for 12 months in prediabetics
Secondary Outcome Measures
NameTimeMethod
Reduction in BMI and waist circumferenceEvery three months for 12 months
Reduction in dose and frequency of anti diabetes medicines in diabeticsAt the beginning of study and after one year
Reduction in HOMA-IRAt the beginning and after one year
Diabetes remission %After one year of beginning the study

Trial Locations

Locations (1)

Professors cabin, Department of Community Medicine, BJ Government Medical College

🇮🇳

Pune, MAHARASHTRA, India

Professors cabin, Department of Community Medicine, BJ Government Medical College
🇮🇳Pune, MAHARASHTRA, India
Dr Jagannath Vinayak Dixit
Principal investigator
9922994777
drjvdixit@gmail.com

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.