NCT05341687已完成不适用
Prognostic Value of Respiratory System Compliance Under VV-ECMO on 180-day Mortality in Patients With COVID-19 Associated Acute Respiratory Distress Syndrome (CARDS)
Central Hospital, Nancy, France1 个研究点 分布在 1 个国家目标入组 122 人开始时间: 2020年1月3日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 122
- 试验地点
- 1
- 主要终点
- Vital status (dead or alive)
研究概览
简要总结
Mortality of patients with COVID-19 associated acute respiratory distress syndrome (CARDS) treated with veno-venous extra-corporal membrane oxygenation (vv-ECMO) is increasing over time since the beginning of the COVID-19 pandemic. The objectives were to retrospectively describe over the first ten days after vv-ECMO implantation, the ventilatory management of CARDS and to assess the impact of static respiratory system compliance (CRS) on the first day of vv-ECMO on 180-day mortality.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with ARDS secondary to COVID-19 pneumonia requiring ECMO-VV support, hospitalized in the intensive care units of the CHRU of Nancy, Marseille or Bordeaux between 01/03/2020 and 31/12/
- •Age > 18 years old
排除标准
- •Respiratory parameters not available on ten first day of VV ECMO implantation.
- •Patient refusal to participate in the study
结局指标
主要结局
Vital status (dead or alive)
时间窗: Days, 10.
according to compliance during the first ten days of VV ECMO implantation
次要结局
- Evolution of driving pressure(Days, 10)
- Evolution of PEEP(days, 10)
- Evolution of tidal volume(Days, 10)
研究者
Matthieu KOSZUTSKI
Principal investigator
Central Hospital, Nancy, France
研究点 (1)
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