Competing Risk of Death and End-stage Renal Disease in Incident Chronic Kidney Disease (Stages 3 to 5): the EPIRAN Community-based Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 631
- 主要终点
- annual incidence rate of CKD
研究概览
简要总结
Although chronic kidney disease (CKD) affects a growing number of people, epidemiologic data on incident CKD in the general population are scarce. Screening strategies to increase early CKD detection have been developed.
Methods: From a community-based sample of 4,409 individuals residing in a well-defined geographical area, investigators determined the number of patients having a first serum creatinine value ≥1.7 mg/dL and present for at least 3 months that allowed us to calculate an annual incidence rate of CKD (stages 3 to 5). CKD (stages 3 to 5) was defined by estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m2. Investigators also described the primary care, outcomes and risk factors associated with outcomes using competing risks analyses for these CKD patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •>= 18 years
- •first serum creatinine value ≥1.7 mg/dL reached after January 1st, 2004
- •and present for at least 3 months
- •residing in the given geographical area (the Urban Community of Greater Nancy (UCGN))
排除标准
- •<18 years
- •prevalent CKD patient : CKD diagnosis before January 1st, 2004
- •patients on dialysis or renal transplanted
- •refusal of participation
结局指标
主要结局
annual incidence rate of CKD
时间窗: inclusion
number of patients residing in a well-defined geographical area having a first serum creatinine value ≥1.7 mg/dL after January 1st, 2004 and still present for at least 3 months
次要结局
- dialysis initiation(through study completion, 6 year after study start)
- death(through study completion, 6 year after study start)
- management of CKD patients(through study completion, 6 year after study start)