NCT05730855已完成不适用
Diagnostic Accuracy of lncRNA DQ786243 and miRNA146a in Saliva of Oral Potentially Malignant Lesions
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- salivary expression of lncDQ786243 in OLP, Leukoplakia, control
研究概览
简要总结
The aim of this study is to evaluate salivary expression of lncRNA DQ786243 as a potential marker for diagnosis of oral potentially malignant lesions compared to normal controls and its effect on salivary expression of miRNA146a.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •participants will be divided into 3 groups:
- •Group I: patients suffering from oral lichen planus Group II: patients suffering from leukoplakia Group III: healthy subjects who are systemically free, non-smokers, and not suffering from any oral mucosal lesions.
排除标准
- •Subjects taking any drugs inducing any changes that could affect the salivary flow.
- •Pregnant females.
- •Subjects have any allergies, infectious diseases or active dental abscesses during one month before saliva sampling.
- •Patients receiving any drugs related to the oral lesions in the past 6 month prior to sample collection.
结局指标
主要结局
salivary expression of lncDQ786243 in OLP, Leukoplakia, control
时间窗: 2 months
次要结局
- salivary expression of miRNA146a in OLP, Leukoplakia, control(2 months)
研究者
研究点 (1)
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