A Study to Evaluate Efficacy and Safety of CS-3150 in Patients With Severe Hypertension (Grade III)

DAIICHI SANKYO Co.,Ltd.0 个研究点目标入组 20 人开始时间: 2016年6月6日最近更新: 2023年10月17日

适应症

试验速览

阶段: 3 期
状态: 已完成
发起方: DAIICHI SANKYO Co.,Ltd.
入组人数: 20

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

The efficacy and safety of CS-3150 titrated from 2.5 mg to 5 mg were investigated in patients with hypertension of grade III after 8 weeks. The change in sitting blood pressure was significantly reduced in both systolic blood pressure and diastolic blood pressure, confirming a clear antihypertensive effect. There were no safety issues.

研究设计

研究类型: Interventional

入排标准

年龄范围: >= 20age old 至 <= 80age old（—）
性别: All

入选标准

•1)Male and female subjects aged 20 to 80 years at informed consent
•2) Subjects with hypertension, who do not receive any antihypertensive drugs or receive antihypertensive drugs (except for potassium-sparing diuretics) during run-in period (Sitting SBP >= 180 mmHg or Sitting DBP >= 110 mmHg)

排除标准

•1)Suspected Hypertensive emergency
•2)Secondary hypertension or malignant hypertension
•3)Diabetic nephropathy
•4)Serum potassium level < 3.5 or >= 5.1 mEq/L (< 3.5 or>= 4.8 mEq/L if receive RA inhibitor)
•5)eGFR < 60 mL/min/1.73 m^2.

研究者

发起方

DAIICHI SANKYO Co.,Ltd.

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