Study for Screening of Chinese Patent Drugs in the Rehabilitation Treatment of novel coronavirus pneumonia (COVID-19)
- Conditions
- ovel coronavirus pneumonia (COVID-19)
- Registration Number
- ITMCTR2000003279
- Lead Sponsor
- Hubei Provincial Hospital of TCM
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
(1) Patients who meet the COVID-19 diagnostic criteria and discharge standards, but the later SARS-CoV-2 virus nucleic acid test is positive;
(2) Aged 18 to 70 years old;
(3) Signed informed consent.
1. Accompanied by severe basic diseases affecting survival, including uncontrolled clinically significant heart, kidney, digestive, blood diseases, neuropsychiatric diseases, immune diseases, metabolic diseases, malignant tumors, severe malnutrition, etc.;
2. Unstable angina pectoris or myocardial infarction in the last 1 month;
3. Allergic constitution, allergic to the drug ingredients involved in the treatment program;
4. Pregnant or nursing women;
5. Mental state cannot cooperate, suffer from mental illness, have no self-control, cannot express clearly;
6. Participating in other clinical trials;
7. According to the judgment of the researchers, patients who will be included in the group will have complications or poor compliance, which will affect the efficacy and safety evaluation.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Qualitative RT-PCR results of SARS-CoV-2 nucleic acid of oral / nasopharyngeal swabs, anal swabs, sputum and blood ;
- Secondary Outcome Measures
Name Time Method Detection and analysis of molecular immunogram;Plasma cytokine assay;SARS-CoV-2 virus content in blood cell;Isolation and cultivation of SARS-CoV-2 virus;2019-nCoV Antibody Test;Sars-cov-2 viral load levels in Oral / nasopharyngeal swab, anal swab, sputum, blood;Detection of SARS-CoV-2 N and S proteins in pharyngeal swabs and saliva;lung CT;Leukocyte, neutrophil, lymphocyte counts;Clinical symptoms by Visual analogue scale (VAS);PBMC lymphocyte flow cytometry;