NCT01019291撤回不适用
Aldehyde and Nitrogen Dioxide at Homes: Measurement of the Exposure and Their Role on Allergic Asthma
University Hospital, Strasbourg, France1 个研究点 分布在 1 个国家开始时间: 2009年11月25日最近更新:
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- 试验地点
- 1
研究概览
简要总结
It seems that the aldehydes and NO2, at the levels found indoor, could be the aggravating factors for an allergic response. However this effect has not been demonstrated. The investigators plan to study the effect of exposure to standard doses of these pollutants on the bronchial reactivity as measured by bronchial challenge tests with dust mite extract in volunteers asthmatic, allergic to house dust mite.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •M/F 18-50 years of age
- •History of intermittent HDM allergic asthma-FEV1 > 80%
- •Non smokers or smokers with smoking < 10 PY
排除标准
- •Persistent asthma and FEV1<80%
- •Allergic to pets and pets at home
研究组 & 干预措施
NO2
Experimental
NO2 400 µg/m3
干预措施: Formaldehyde and NO2 (Exposure to indoor pollutants) (Other)
Formaldehyde
Experimental
Formaldehyde 100 µg/m3
干预措施: Formaldehyde and NO2 (Exposure to indoor pollutants) (Other)
NO2 + Formaldehyde
Experimental
mixture of Formaldehyde and NO2
干预措施: Formaldehyde and NO2 (Exposure to indoor pollutants) (Other)
Placebo
Placebo Comparator
干预措施: Placebo (Exposure to indoor pollutants) (Other)
研究者
研究点 (1)
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