The effect of Cassia Fistula in pediatric constipatio

Phase 3

• Conditions: Constipation.; Constipation (atonic) (simple) (spastic)

• Registration Number: IRCT201303196932N2
• Lead Sponsor: Babol University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

children between 2 to 15 years old who have at least 2 or more of the followings: Less than 2 defections in the toilet each week: More than 1 episode of fecal incontinence per week; History of retentive posturing or excessive volitional stool retention; History of painful or hard bowel movements; Presence of a large fecal mass in the rectum; History of large diameter stools that may obstruct the toilet; children with inclusion criteria will be seen by a pediatric gastroenterologist to provide complete functional constipation criteria. If the history and physical examination, functional constipation is not proved or questioned, anorectal manometry is performed.If confirmed in functional constipation and the tendency of parents, children are enrolled.
Exclusion criteria: any symptom of organic constipation in the history or physical examination; any evidence of organic constipation in anorectal manometry; fecal impaction on physical examination that cannot be removed; presence of other chronic diseases that lead to long-term use of drugs; Long-term consumption of drugs that can cause constipation; intolerance of drinking cassia syrup (nausea and vomiting or severe abdominal pain or allergic symptoms); no compliance, the patient's unwillingness to continue treatment; If any complication due to drugs (such as crampy abdominal pain; probable electrolyte disorder signs due to severe diarrhea (potassium imbalance); muscle weakness or palpitation;and facial and limbs edema; or other complications that are possibly related to drugs) happen, the treatment will be discontinued the adverse effect are recorded.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
umber of defications per week. Timepoint: before intervention and 7, 14, 21 ,28 days after begining of the intervention. Method of measurement: questionairre.;Intensity of pain of defication. Timepoint: before intervention and 7, 14, 21,28 days after begining of the intervention. Method of measurement: questionairre and VAS.;Intensity of stiffness of the stool in defication. Timepoint: before intervention and 7, 14, 21,28 days after begining of the intervention. Method of measurement: questionairre and VAS.