sing saliva and Oral smears for early detection of Oral Cancer
Not Applicable
Completed
- Conditions
- Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynxHealth Condition 2: null- Oral Squamous Cell Carcinoma
- Registration Number
- CTRI/2017/02/007917
- Lead Sponsor
- Deepika Rathna M
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 48
Inclusion Criteria
Case: Patients diagnosed of Oral Squamous Cell carcinoma, yet to undergo any therapeutic intervention
Control: Healthy age and gender matched individuals
Exclusion Criteria
Patients diagnosed with Parkinsonâ??s disease
Patients with history of other malignancies
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Increased Salivary Biomarker ( s-adenosyl methionine) in patients with oral squamous cell carcinomaTimepoint: 1
- Secondary Outcome Measures
Name Time Method - Establishment of baseline Salivary SAM concentration in local population <br/ ><br>- Elevated SAM concentration in Saliva of OSCC patients compared to normal counterpart <br/ ><br>- Elevated SAM in patients with Increased N:C ratio <br/ ><br>- 95% accurate prediction of OSCC by evaluation of N:C ratio and Salivary SAM <br/ ><br>Timepoint: 1