Cytokine removal in kidney transplantatio
Phase 1
- Conditions
- Kidney transplantation from deceased donors.Surgery
- Registration Number
- ISRCTN13698207
- Lead Sponsor
- niversity of Cambridge
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Ongoing
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
1. Patients receiving a kidney from donation after brain death (DBD) and/or donation after circulatory death (DCD) donor =50 years
2. Transplant recipients aged =18 years
3. Patients undergoing a 1st or 2nd kidney transplant
4. Patients who have given written informed consent
5. Patients that are receiving renal replacement therapy
Exclusion Criteria
1. Patient receiving a kidney from DCD and DBD donor <50 years old
2. Patients receiving a 3rd or subsequent kidney transplant
3. Patients receiving multi-organ transplants e.g. simultaneous pancreas-kidney transplantation
4. Patients receiving dual kidney transplants
5. Paediatric en-bloc kidney transplants
6. Patients that are pre-dialysis
7. Kidneys will complex vascular anatomy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Inflammatory and immune gene expression measured in cortical biopsy from the kidney 60 minutes post-transplant
- Secondary Outcome Measures
Name Time Method