Investigation on the Effect of Smoking on the Expression of Pro- and Anti-thrombotic, Anti-oxidative, and Inflammatory Markers in Humans
Terminated
- Conditions
- SmokingInflammationThrombosis
- Registration Number
- NCT02198937
- Lead Sponsor
- University of Zurich
- Brief Summary
Investigation on the effect of smoking on thrombus formation in humans. The expression of pro- and anti-thrombotic, anti-oxidative, and inflammatory markers will be assessed in 25-50 year old healthy smokers and non-smokers. The investigators are interested in possible differences between the two groups.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
- Smoker
- Non-smokers
Exclusion Criteria
- Disease
- Pregnancy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Expression of pro- and anti-thrombotic, anti-oxidative, and inflammatory markers in blood Single time point, no follow-up (cross sectional)
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link smoking to altered expression of pro- and anti-thrombotic markers in humans?
How do inflammatory biomarkers in smokers compare to non-smokers regarding thrombosis risk and oxidative stress?
Are there specific anti-oxidative pathways that could serve as therapeutic targets for smoking-related thrombosis?
What adverse events are associated with smoking cessation interventions in middle-aged adults with thrombotic risk factors?
How does the expression profile of thrombosis-related markers in NCT02198937 compare to other observational studies on cardiovascular disease?
Trial Locations
- Locations (1)
University Hospital
🇨🇭Zurich, Switzerland
University Hospital🇨🇭Zurich, Switzerland