Comparison of anticandidal efficacy of Silver Diamine Fluoride and Chlorhexidine in children with severe early childhood caries

Phase 4

• Conditions: Severe early childhood caries.; Dental caries, unspecified; K02.9

• Registration Number: IRCT20201104049255N1
• Lead Sponsor: Babol University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 May 2021

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Children younger than 5 years old
Children with severe early childhood caries (according to defs scale)
Healthy children with no systemic condition
Children with positive Candida albicans culture of dental plaque

Exclusion Criteria

Children who underwent either antibiotic, antifungal or fluoride therapy (systemic or topical) within the last 1 month prior to the study
children with orthodontic or prosthodontic appliances
special health care needs children
children with no written informed consent granted

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Dental plaque Candida albicans colony count 2 and 30 days after treatment. Timepoint: Dental plaque colony count of Candida at beginning of the study (before the intervention) and 2 and 30 days after treatment with Silver Diamine Fluoride or Chlorhexidine. Method of measurement: candida colony count.