Efficacy of Gokshuradi Vati orally with and without administration of Ashwagandhadi tail Uttarbasti in the mangement of Kshinashukra (Oligospermia)-a open labelled randamized clinical camparative clinical trial
试验速览
- 阶段
- 2/3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- To increase sperm count and sperm motility of patient of Kshinashukra.
研究概览
简要总结
The trial is randomized clinical trial to evaluate the role of Gokshuradi vati orally with and without administration of Ashwagandhadi Taila Uttarabasti in the management of kshinshukra(Oligospermia). Total 30 patient will be enrolled in the study. Selected patient will be divided into 2 groups on the basis of computer-generated randomization. In this study Gokshuradi vati 4 tab. BD before meal each of 500mg will be given orally with anupan of godugdha for 8 weeks and Ashwagandhadi taila uttarbasti 20ml early morning for 14 days.In another group Gokshuradi vati 4tab.BD before meal orally with anupana of godugdha each of 500mg.for 8 weeks. follow-ups will be carried out at 15 days interval for 2month after treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 21.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- Male
入选标准
- •1 Male patients with age between 21 to 40 years 2 Patients having Sperm count less than 15 million per ml According to WHO 2021 and or Low sperm motility less than 50 percent SLP Sperm like particles 3 Patient with or without clinical presentation of Kshinashukra Daurbalya, Mukhashosha.
排除标准
- •1 Patients with sperm count more than 15 million per ml 2 Patients with age below 21 and above 40 years 3 Patients of aspermia and azoospermia 4 Patients suffering from Varicocele, accessory sex gland infection, STD, Systemic diseases like chronic renal failure CRF, Uncontrolled Hypertension BP more than150per90 mmHg, Diabetes mellitus RBS more than140 mg per dl 5 Genetic disorders like Klinfelter syndrome.
- •6 Patients taking treatment for major psychiatric illness 7 History of previous medication and trauma leading to oligospermia 8 Patients having Hematuria Blood in the urine, Chronic Cystitis, UTI, Kidney Stone, Bladder Stones 9 Known case of Cardiac Diseases History of Myocardial infraction, Ischemic heart disease 10 Patient suffering from Urethral Stricture, Phimosis, Meatal Stenosis, Hypospadiasis, Epispadiasis.
结局指标
主要结局
To increase sperm count and sperm motility of patient of Kshinashukra.
时间窗: Group A- 16 weeks | Group B- 16 weeks
次要结局
- To treat infertility due to male factor and have healthy progeny.(2 To improve the quality of life of infertile couple.)
研究者
Digvijay Tanaji Patil
Institute of Teaching and Research in Ayurveda Jamnagar