Establishment of a (18)F-florbetaben PET normative database of Japanese nondemented subjects and its application to detection of early cortical amyloid deposition - Establishment of a (18)F-FBB PET normative database of Japanese nondemented subjects

Keio University School of Medicine0 个研究点目标入组 120 人开始时间: 2016年12月27日最近更新: 2023年10月17日

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•(1) Women who are or may be pregnant, or breast-feeding women (2) History of alcohol abuse (3) History of receiving epileptic treatment (4) Education period less than or equal to 6 years (5) The subject is taking antidepressants or psychotropic drugs or receiving the long-time administration of sedative agents. (6) History of neuropsychiatric disorders that are known to cause cognition (7) The subject is critically ill and/or medically unstable (e.g. volunteers with advanced hepatic or renal dysfunction, or with severe endocrine metabolic disease) (8) The subject whose MRI shows that ischemic white matter disease and/or lacunar infarctions are beyond normal range according to the guideline from the Japan Brain Dock Society (9) The subject whose MRI shows space-occupying lesions, unexpected cerebrovascular disease, neurodegenerative disease or congenital abnormality in the brain (10) History of high amount of radiation exposure

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