Effects of a sugar-reduced diet on bleeding of probing after periodontal therapy

Not Applicable

• Conditions: Chronic periodontitis; K05.3

• Registration Number: DRKS00026699
• Lead Sponsor: Abteilung für Parodontologie, Oralmedizin und Oralchirurgie, CharitéCentrum für Zahn-, Mund- und KieferheilkundeCharité – Universitätsmedizin Berlin

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-10-14
• Study Completion: 2022-08-24
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

age 18-75 years
western-diet (daily consumption of sugar)
planned periodontal therapy
diagnosis: generalized periodontitis, grade A-B, stage I-III, BOP >30%, last subgingival debridement >2 years ago, smoking < 5 cigarettes/day, BMI 18-30, mild systemic disease without known effects on periodontal inflammation

Exclusion Criteria

periodontitis stage IV, grade C, diabetes (treated with medication), treatment with anticoagulant, antibiotics in last 3 months, cortisol, pregnancy, lactation, severe systemic diseases, eating disorder, severe psychological disorders, participating in another study, orthodontic treatment/appliance, xerostomia, smoking >5 cigarettes/day, ongoing dental treatment other than periodontal intervention)

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bleeding on Probing <br>at baseline, after 4 and 8 weeks of periodontal treatment, with a pressure-sensitive periodontal probe

Secondary Outcome Measures

Name	Time	Method
PISA (periodontal inflamed surface area)<br>Periodontal pocket debt <br>plaque index<br>gingival bleeding index<br>bmi<br>waist circumference<br>weight<br>BIA<br>FFQ<br>OHIP-21<br>HbA1c<br>at baseline, 4 and 8 weeks after treatment <br>continuous Glucose monitoring (2 weeks before and 2 weeks after treatment); microbiological and salivary samples; diatary diary