Can seaweed supplementation reduce cardiovascular disease risk?

Not Applicable

Completed

• Conditions: cardiovascular disease; type 2 diabetes; hypercholesterolaemia; Diet and Nutrition - Other diet and nutrition disorders; Metabolic and Endocrine - Diabetes; Cardiovascular - Other cardiovascular diseases; Alternative and Complementary Medicine - Other alternative and complementary medicine

• Registration Number: ACTRN12617001039370
• Lead Sponsor: Monash University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-07-17
• Study Completion: 2018-12-04
• Last Update Posted: 15 July 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 34

Inclusion Criteria

Body mass index from 27 to 35 kg/m2 (25 to 35 kg/m2 for people of Asian background)
Fasting LDL cholesterol level above 2.0 mmol/

Exclusion Criteria

Gastrointestinal issues that may affect the absorption and intestinal actions of the polyphenols,
Taking medication for cholesterol or blood pressure control or any other medications that may influence results.
Taking other natural health products known to impact on polyphenols e.g. fish oil,
Women who are breastfeeding or pregnant,
Individuals with liver/thyroid issues,
Having undergone major surgery in the past 6 months,
Consuming more than 4 standard drinks per day, or 14 standard drinks per week,
Cigarette smoking.
Having an implanted cardiac defibrillator.
Individuals with depression, anxiety or dementia (cognitive aspect only)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in fasting LDL cholesterol level as assessed by automated analyser (Indiko).[Comparing baseline and 12 weeks post commencement of the intervention]