NCT00765024已完成3 期
Efficacy and Safety of Ivermectin Versus Albendazole for Chronic Strongyloidiasis
适应症
干预措施
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- cure rate
研究概览
简要总结
A prospective controlled trial to compare the efficacy and safety of 7-day albendazole, single dose ivermectin, and 2-single dose ivermectin in 72 patients with chronic strongyloidiasis will be conducted at Siriraj Hospital, Bangkok, Thailand.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with positive strongyloides larva in the stool
排除标准
- •Pregnancy
- •Lactating women
- •Known allergy to any study drug
研究组 & 干预措施
Albendazole
Active Comparator
Albendazole for 7 days
干预措施: Albendazole (Drug)
ivermectin
Experimental
ivermectin 200 mcg/kg single dose
干预措施: ivermectin (Drug)
ivermectin 2 doses
Experimental
ivermectin 200 mcg/kg two doses in 2 weeks
干预措施: ivermectin (Drug)
结局指标
主要结局
cure rate
时间窗: 1 year
次要结局
- safety(1 year)
研究者
研究点 (1)
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