An Exploratory Study of the Efficacy and Safety of Minimally Invasive Supraporoidal Drainage for Advanced Neovascular Glaucoma
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Ocular biological parameters
研究概览
简要总结
To explore the efficacy and safety of minimally invasive suprachoroidal drainage for the treatment of advanced neovascular glaucoma
详细描述
To explore the efficacy and safety of minimally invasive supraporcular drainage in the treatment of advanced neovascular glaucoma, and to record the various basic diseases, ocular conditions, lifestyle, inflammatory markers and other parameters of NVG patients. To compare the safety and efficacy of new surgical methods and traditional surgical methods in order to find an effective treatment for neovascular glaucoma
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Advanced (angle-closure) neovascular glaucoma with poorly controlled intraocular pressure (IOP > 21mmHg) after medical or surgical treatment
排除标准
- •Various other types of glaucoma (including primary open-angle glaucoma, primary open-closed glaucoma, normal tension glaucoma, juvenile glaucoma, congenital glaucoma, other special types of glaucoma, etc.)
- •Eye infection within two weeks before surgery
- •Non-glaucomatous intraocular diseases that affect intraocular pressure (choroidal hemorrhage or detachment, retinal detachment, lens subluxation, thyroid eye disease, clinically significant macular edema, eye tumors, etc.)
- •Visual acuity of non-study eyes < 0.05
- •Congenital or acquired factors lead to ciliary body anatomical abnormalities
结局指标
主要结局
Ocular biological parameters
时间窗: 1 day, 1 week, 1 month, 3 months, and 6 months after surgery
intraocular pressure
The success rate of surgery was evaluated according to the specific value of intraocular pressure after surgery
时间窗: 1 day, 1 week, 1 month, 3 months, and 6 months after surgery
Complete success was defined as IOP within the normal range with no drug dependence, conditional success was defined as IOP within the normal range with drug dependence, and failure was defined as the rest
Surgical outcome measures
时间窗: 1 day, 1 week, 1 month, 3 months, and 6 months after surgery
use of intraocular pressure lowering drugs
次要结局
- Surgical outcome measures(1 day, 1 week, 1 month, 3 months, and 6 months after surgery)
- The effective rate of surgery was evaluated according to the amplitude of IOP reduction after surgery and the change in the number of IOP-lowering drugs(1 day, 1 week, 1 month, 3 months, and 6 months after surgery)