Neurophysiological Effects of Percutaneous Electrolysis Related to Endogenous Pain Modulation
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- University of Salamanca
- Enrollment
- 54
- Locations
- 2
- Primary Endpoint
- Changes from baseline in Pressure Pain Thresholds (PPT)
Study Overview
Brief Summary
Percutaneous electrolysis is based on the application of a galvanic current through an acupuncture needle. The underlying mechanisms that explain the efficacy of this technique are not completely well understood. The objective is to delve into the neurophysiological analgesic effects of percutaneous electrolysis. Participants will be assigned to one of three intervention groups. The analgesic effects of the technique will be evaluated by means of variables related to endogenous pain modulation.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Basic Science
- Masking
- Double (Participant, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 40 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Asymptomatic subjects
- •Signature of the informed consent
Exclusion Criteria
- •Fear of needles
- •Any pathology or process that causes pain
- •Neurological, rheumatologic, cardiovascular or metabolic diseases
- •Cutaneous alterations and cognitive or sensitivity disorders
- •Pregnancy
- •Recent intake of alcohol or caffeine
- •Vigorous physical activity on the day of testing
Outcomes
Primary Outcomes
Changes from baseline in Pressure Pain Thresholds (PPT)
Time Frame: Baseline and immediately after the intervention
PPTs will be measure by algometry in the common extensor tendon of the epicondyle, bicipital groove and tibialis anterior muscle (all of the right side).
Secondary Outcomes
- Changes from baseline in Temporal Summation (TS)(Baseline and immediately after the intervention)
- Changes from baseline in Conditioned Pain Modulation (CPM)(Baseline and immediately after the intervention)
Investigators
Sergio Varela Rodríguez
PhD candidate
University of Salamanca