Effects of Different Methods of Prescription and Monitoring of Resistance Training Intensity on Muscle Strength, Body Composition, and Psychological Well-being in Survivors of Breast Cancer
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 61
- 试验地点
- 1
- 主要终点
- Muscular strength
研究概览
简要总结
The goal of this clinical trial is to compare the effects of three different methods of prescribing and monitoring resistance training intensity on muscle strength, body composition, quality of life, fatigue, anxiety, and depression in breast cancer survivors.
详细描述
Breast cancer survival rates have significantly increased in recent years, highlighting the importance of effective interventions to address the long-term consequences of cancer and its treatments. Breast cancer survivors often experience muscle weakness, changes in body composition, fatigue, and psychological distress, which can negatively impact their quality of life. Resistance training has been widely recognized as a safe and effective strategy to counteract these effects, improving muscle strength, body composition, and psychological well-being.
Despite its benefits, the optimal method for prescribing and monitoring resistance training intensity in breast cancer survivors remains unclear. Traditional methods based on one-repetition maximum (1RM) testing may not fully account for individual variations in fatigue and performance. Alternative approaches, such as load-velocity relationships, allow for more precise and real-time adjustments to training intensity, potentially optimizing outcomes.
This randomized controlled trial aims to compare the effects of three different methods of resistance training intensity prescription and monitoring on muscle strength, body composition, quality of life, fatigue, anxiety, and depression in breast cancer survivors. The findings will contribute to developing evidence-based exercise guidelines, enhancing rehabilitation strategies and overall well-being in this population.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •To be >18 years old.
- •To have a breast cancer diagnosis.
- •To have finished chemotherapy, radiotherapy and/or surgery up to 10 years prior to the beginning of the study.
排除标准
- •To present metastatic breast cancer.
- •To have a planned surgery for breast reconstruction within three months after the start of the study.
- •To present any absolute contraindication for exercising.
研究组 & 干预措施
Daily load-velocity-based training intensity adjustment
At the beginning of the training session, the one-repetition maximum (1RM) will be estimated based on the individual's load-velocity relationship, using the general velocity associated with the 1RM for the exercises included in the session. Additionally, during the training sessions, intensity will be monitored, and load will be adjusted in real time by movement velocity.
干预措施: Daily load-velocity-based training intensity adjustment. (Behavioral)
Training intensity prescription based on an initial 1RM estimation using load-velocity relationship.
In the first training session, the one-repetition maximum (1RM) will be estimated based on the individual's load-velocity relationship, using the general velocity associated with the 1RM for the exercises included in the session. This 1RM will be used to prescribe exercise intensity throughout the intervention.
干预措施: Training intensity prescription based on an initial 1RM estimation using load-velocity relationship (Behavioral)
Traditional training with intensity prescription based on 1RM testing.
The traditional training group will follow a training program using the traditionally employed methodology for assessing and prescribing training intensity in breast cancer survivors. This methodology is based on an initial 1RM estimation conducted through a 1RM test, which will be used to prescribe the training load throughout the intervention.
干预措施: Traditional training with intensity prescription based on 1RM testing. (Behavioral)
结局指标
主要结局
Muscular strength
时间窗: Change from baseline to week 8
The main variable of the present study will be muscle strength, assessed by determining peak isometric strength in the bench press and squat exercises using force platforms.
次要结局
- Muscle function (5STS)(Change from baseline to week 8)
- Height (scale)(Baseline)
- Body weight (InBody 770)(Change from baseline to week 8)
- Total fat mass (InBody 770)(Change from baseline to week 8)
- Fat percentage (InBody 770)(Change from baseline to week 8)
- Fat-free mass (InBody)(Change from baseline to week 8)
- Handgrip strength(Change from baseline to week 8)
- Visceral fat mass level (InBody)(Change from baseline to week 8)
- Health-related quality of life (FACT-B)(Change from baseline to week 8)
- Cancer-related fatigue (FACIT-F)(Change from baseline to week 8)
- Anxiety and depression (HADS)(Change from baseline to week 8)
- Patient global impression of change(Week 8)
研究者
Alberto Soriano-Maldonado
PhD
Universidad de Almeria