To Compare Air vs 2% lignocaine as Endotracheal cuff Insufflation medium and its effect on Post-operative sore throat.

Not yet recruiting

• Conditions: Measurement and Monitoring,

• Registration Number: CTRI/2022/10/046164
• Lead Sponsor: ESIC Medical College and PGIMSR

Brief Summary

Thisresearch study will be conducted in patients planned for elective surgery underGeneral anaesthesia. This is a comparative study of Cuff pressure monitoringwhen ETT cuff is insufflated with Air vs 2%Lignocaine.Multiple parameters willbe monitored. Previous such studies indicated that 2% Lignocaine is better interms of variation in cuff pressure and it’s effect on Post-Operative sorethroat.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-03-10
• Study Start: 2022-10-17

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• atient with written informed consent â—18-60 yrs.
• of Age â—ASA physical status I-II â—Elective surgery â—Supine Position â—Under General Anaesthesia more than 120mins with Endotracheal Intubation.

Exclusion Criteria

• Patient refusal • Procedures involving soft tissue around airway • ASA III or above •History of known allergic to local anaesthetics • History of recent upper respiratory tract infection • History of present COVID-19 infection • Laryngeal disease/surgery • H/O smoking • Those requiring insertion of nasogastric tube.
• • Those requiring more than 1 attempt to achieve tracheal intubation.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cuff Pressure using AG-Cufffill monitor in CmH2O	At start of surgery,every 15min till end of suregry, and before removing endotracheal tube(end of surgery).

Secondary Outcome Measures

Name	Time	Method
Heart rate , Blood pressure, Oxygen saturation using standard monitors	At start of surgery,every 15min till end of suregry, and before removing endotracheal tube(end of surgery).
Incidence of Post operative sore throat	After surgery at 30 min,12 hour,24hours
Variation in Cuff volume	At start of surgery and end of surgery

Trial Locations

Locations (1)

ESIC Medical College and PGIMSR; 🇮🇳 Chennai, TAMIL NADU, India

ESIC Medical College and PGIMSR

🇮🇳Chennai, TAMIL NADU, India

DrJethroben KevinR

Principal investigator

8056034998

jethrobenkevin@gmail.com