NCT00780195已完成不适用
Metabolic Adaptations to Diabetes
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 16
- 主要终点
- catecholamines
研究概览
简要总结
We do not know why diabetic patients cannot protect themselves against low blood sugar. Therefore, in this study, we will perform a comprehensive assessment of the body's response to low blood sugar by measuring changes in blood hormones, blood sugar production, and nerve signals.
详细描述
Morning and afternoon hypoglycemic episodes of 70, 60, or 50 mg/dl produce increased blunting of subsequent counterregulation dependent upon the depth of preceding hypoglycemia. We wanted to test this hypothesis in healthy African American individuals to determine if there is a difference in their responses to varying depths of hypoglycemia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy males and females aged 18-40 yrs with no family history of diabetes mellitus.
- •All prospective volunteers will have routine blood tests to screen for biochemical, hormonal and hematological abnormalities.
- •Female volunteers will also undergo an HCG urine pregnancy test.
排除标准
- •Prior or current history of poor health
- •Abnormal results following blood and physical examination
- •Pregnancy
结局指标
主要结局
catecholamines
时间窗: 2 hours
次要结局
未报告次要终点
研究者
Steve Davis
Department Chair
Vanderbilt University
相似试验
已完成
不适用
Metabolic Adaptation to DiabetesType 2 DiabetesNCT00732862Vanderbilt University15
已完成
不适用
Glycemic control among diabetic patients complicated with sarcopenia and frailty.diabetes mellitusJPRN-UMIN000040689Juntendo University, Juntendo Tokyo Koto Geriatric Medical Center140
已完成
不适用
Diabetes mellitus and abnormal glucose tolerance development after gestational diabetesISRCTN24165302St Carlos Hospital (Hospital Clínico San Carlos) (Spain)250
招募中
早期 1 期
Effect of C-peptide on Hypoglycemic CounterregulationType 1 DiabetesHypoglycemiaNCT06470295University of Cincinnati38
招募中
不适用
A digital health program combined with an activity tracker to improve llifestyle behavior.HbA1c, diabetes type 2, lifestyle behavior, activity monitoring, feedback. Leefstijl, zelfmeting van beweging, feedback.NL-OMON28551Hanze University of Applied Sciences, research group Healthy ageing, Allied health care and Nursing.96