Effects of Ultrasound Guided Erector Spinae Plane Block in Radical Prostatectomy Surgery on Pain and Surgical Stress Response
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Erector Spinae Plane Block
- Sponsor
- Istanbul Medeniyet University
- Enrollment
- 46
- Locations
- 1
- Primary Endpoint
- prolactin
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
Our study aimed to examine the effects of ultrasound guided erector spinae plane block in radical prostatectomy surgery on pain and surgical stress response, to reduce adrenocortical and sympathetic discharge due to anesthesia and surgery, and to reduce peroperative opioid analgesic consumption.
Detailed Description
In this study 46 patients between the ages of 30-74, American Society of Anesthesiologists (ASA) score I-II and undergoing radical prostatectomy surgery at T.R. Ministry Of Health İstanbul Göztepe Prof. Dr. Süleyman Yalçın City Hospital were included. The patients were randomly divided into two groups as ESPB applied Group B (n=23) and not Group K (n=23). Patient-controlled analgesia (PCA) was initiated in all patients for postoperative analgesia. Patients' demographic data (age, gender, ASA score), intraoperative hemodynamic data, intraoperative and postoperative additional narcotic consumption, postoperative Numeric Rating Scale (NRS) scores (postoperative 0, 5 and 20 minutes and Then, 1, 3, 6, 12, 18 and 24 h), postoperative nausea-vomiting scores and possible complications related to block and / or surgery were recorded.Intraoperative MAP, HR, SpO2, BIS values of patients in both groups were recorded every 5 minutes. Blood glucose, insulin, cortisol, prolactin and C-reactive protein (CRP) were studied three times; preop morning at 6:00, intraoperative when surgical incision closing and postoperative 24h. in order to evaluate the surgical stress response in the patients.
Investigators
Damla Turan
Principal Investigator
Istanbul Medeniyet University
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •coagulopathy
- •local anesthetic
- •drug allergy
- •long hospitalization history,
- •hormone disorder
- •advanced organ failure
- •history of steroid use
- •vertebral anomalies
- •mental retardation
Outcomes
Primary Outcomes
prolactin
Time Frame: postoperative 24 hours.
µg/L
cortisol
Time Frame: postoperative 24 hours.
µg/dL
Numeric Pain Scale
Time Frame: postoperative 24 hours.
Between 1-10. 1: no pain, 10: worst possible pain
insulin
Time Frame: postoperative 24 hours.
µIU/mL
C-reactive protein
Time Frame: postoperative 24 hours.
mg/L
Blood glucose
Time Frame: postoperative 24 hours.
mg /dL
Secondary Outcomes
- Remifentanil Consumption Speed(3 hours)