Comparative Evaluation Of Free Dried Bone Allograft (FDBA) With and Without i-PRF (Injectable Platelet Rich Fibrin) In The Treatment of Human Intrabony Defects- A Clinico-Radiographic Study

Group A (FDBA Group): A patient meeting the inclusion criteria from the Periodontology department was inducted into the study. After informed consent, Phase 1 therapy was completed, followed by re-evaluation and recording of Relative Attachment Level (RAL).

• Surgical Protocol:
• Intra-oral asepsis using 0.2% chlorhexidine and extra-oral asepsis with povidone-iodine.
• Crevicular incision and reflection of a full-thickness mucoperiosteal flap, preserving interdental tissues.
• Degranulation and root planing confirmed the presence of an intra-bony defect (IBD).
• Freeze-Dried Bone Allograft (FDBA) was procured from the Tissue Bank at Tata Memorial Hospital, mixed with saline, placed, and condensed into the defect.
• Sutures were placed, and patients were recalled for suture removal after one week and for follow-up at 3 and 6 months.

Group B (Fdba with iPRF): A similar protocol was followed for patients in this group, using FDBA with iPRF.

• Surgical Protocol:
• Phase 1 therapy, RAL measurement, asepsis, and flap reflection were conducted as described.
• The defect was filled with FDBA with iPRF, followed by suturing.
• Patients were recalled after 1 week for suture removal and follow-ups at 3 and 6 months.

Postoperative Care for Both Groups:

• Patients were prescribed oral hygiene instructions, antibiotics, and analgesics for 5 days.
• Oral hygiene instructions were reinforced during the 7-day recall visit.

Outcome Measurements: Baseline, 3-month, and 6-month clinical and radiographic assessments were recorded for statistical analysis. Remaining cases for test and control groups were conducted following the same methodology for comparative evaluation.