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临床试验/IRCT20181226042136N1
IRCT20181226042136N1已完成3 期

Comparative of Betamethasone pulse, Methotrexate pulse and Betamethasone Combination using Methotrexate pulse Therapy in Treatment of Severe Alopecia Areata

Esfahan University of Medical Sciences0 个研究点目标入组 36 人开始时间: 待定最近更新:
适应症

试验速览

阶段
3 期
状态
已完成
入组人数
36

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
16 years 至 60 years(—)
性别
All

入选标准

  • The scalp involvement rate more than 50%
  • The disease is resistant to systemic and topical combination therapy
  • The patient is satisfied with the study

排除标准

  • Pregnancy or Breastfeeding
  • Hb less than 9mg/dl
  • Leukocyte less than 4000
  • Platelet less than 100000
  • Potassium is less than 3.5
  • Liver enzymes 2 times more than the reference limit
  • ESR above reference limit
  • Positive Stool Test for Strongyloides stercoralis
  • Positive tests for viral hepatitis
  • Use of any systemic drug a month before the start of the study
  • There is a contraindication for betamethasone (diabetes, high blood pressure, drug allergy, active infection, recent surgery history, osteoporosis, stomach ulcer and psychosis, or depression)
  • Sensitivity to methotrexate

研究者

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