Responsiveness to botulinum toxinum type A in complex regional pain syndrome related fixed dystonia

Completed

• Conditions: post traumatic dystrophy; reflex sympathetic dystrophy; 10028037

• Registration Number: NL-OMON34320
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 56

Inclusion Criteria

CRPS with fixed dystonia of one lower extremity, age between 18 and 50, botulinum toxin naive

Exclusion Criteria

neuromuscular junction diseases, pregnancy/nursing women

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1.Difference between the EDB CMAP amplitudes pre and post BoNT/A injection of<br /><br>the affected CRPS limb and controls.<br /><br>2.Difference between the EDB CMAP amplitudes pre and post BoNT/A injection of<br /><br>the unaffected CRPS limb and controls.<br /><br>3.Difference between the EDB CMAP amplitudes pre and post BoNT/A injection of<br /><br>the affected and unaffected lower limb of patients with CRPS and fixed<br /><br>dystonia. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>not applicable</p><br>