Emesis and Nasal therapy in chronic plaque psoriasis
- Conditions
- Other psoriasis. Ayurveda Condition: MANDALAKUSHTHAH/KAPAJAKUSHTHAH,
- Registration Number
- CTRI/2025/03/083338
- Lead Sponsor
- National Institute of Ayurveda
- Brief Summary
To study the comparative efficacy of Vamana and Nasya karma in the management of Mandal Kustha (Psoriasis), the study will include two groups: a comparator group and an intervention group. in the comparator group, the Vamana procedure with Madanphala Pippali( approximately 10 grams) in Kasaya form will be administered to patients. In the intervention group, Nasya procedure will be performed using Twagadi Taila (0.3 ml in each nostril) for seven consecutive days, with a gap of one day between sessions, repeated three times over a period of 23 days. Changes in PASI Score (psoriasis arear and severity index) and changes in DLQI ( The Dermatology Life Quality Index) along with Compliance of both the procedure Vamana and Nasya in patient will be assessed.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 60
(a) Patient with the classical feature of Mandal kustha (plaque psoriasis) (b) Patient not taking any other medication for Mandal kustha (plaque psoriasis) (c) Patient fit for Vaman and Nasya Karma (d) Patient willing to sign consent form for trial (e) The participant with combined PASI score more than 5 to less than 72 will be included (moderate to severe form).
- (a) Age below the age 18 years & above the age 60 years (b) Patients suffering from systemic disorders as cardiac problem, uncontrolled Diabetes mellitus, uncontrolled Hypertension, paralysis, malignancy, HIV, HBsAg, Leprosy (c) Patient suffering from Psoriatic Arthritis (d) pregnant and lactating mothers.
- (e) patient unfit for Vamana and Nasya Karma.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method changes in PASI Score (psoriasis area and severity index) Baseline, 14th day, and 28th day
- Secondary Outcome Measures
Name Time Method (a) changes in DLOI (The Dermatology Life Quality Index) (b) compliance of both the procedure Vamana & Nasya
Trial Locations
- Locations (1)
National Institute of Ayurveda
🇮🇳Jaipur, RAJASTHAN, India
National Institute of Ayurveda🇮🇳Jaipur, RAJASTHAN, IndiaDr Sarvesh Kumar SinghPrincipal investigator8739860237sarveshksingh21@gmail.com