A Longitudinal Study on the Development and Pathological Changes Among Children and Adolescents With High Myopia in China
试验速览
- 阶段
- 不适用
- 入组人数
- 1,400
- 试验地点
- 1
- 主要终点
- To observe the relationship between the changes of ocular structure parameters and pathological changes among children with high myopia.
研究概览
简要总结
The study aims to observe the relationship between the changes of ocular structure parameters and pathological changes among children and adolescents with high myopia. Environmental factors and family history will also be collected to explore their impacts on high myopia progression.
详细描述
This study aims to observe children and adolescents with high myopia for 3 years, and to collect data of ocular pathological changes, family history and environmental factors so as to understand the natural course and internal laws of the development of high myopia.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 6 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •9 to 18 years old school students in Guangzhou, with either eye had myopia equal or greater than 6.0D
- •Or 6 to 8 years old school students in Guangzhou, with either eye had myopia equal or greater than 3.0D
- •Written informed consent for study participation
- •Be willing to cooperate with the relevant ophthalmological examination and complete the questionnaire.
排除标准
- •None school students in Guangzhou
- •Other contraindications
- •A history of allergy to tropicamide or topical anesthetics
- •Missing ability to give informed consent
结局指标
主要结局
To observe the relationship between the changes of ocular structure parameters and pathological changes among children with high myopia.
时间窗: examine every 12 months, follow up 3 years
examine the ocular pathological changes
次要结局
- To explore the impact of environmental factors and genetic factors on the progression among children and adolescents with high myopia(examine every 12 months, follow up 3 years)
研究者
Yizhi Liu
Clinical Professor,director of Zhongshan Ophthalmic Center
Zhongshan Ophthalmic Center, Sun Yat-sen University