A Longitudinal Study on the Development and Pathological Changes Among Children and Adolescents With High Myopia in China
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- High Myopia
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
- Enrollment
- 1400
- Locations
- 1
- Primary Endpoint
- To observe the relationship between the changes of ocular structure parameters and pathological changes among children with high myopia.
- Last Updated
- 7 years ago
Overview
Brief Summary
The study aims to observe the relationship between the changes of ocular structure parameters and pathological changes among children and adolescents with high myopia. Environmental factors and family history will also be collected to explore their impacts on high myopia progression.
Detailed Description
This study aims to observe children and adolescents with high myopia for 3 years, and to collect data of ocular pathological changes, family history and environmental factors so as to understand the natural course and internal laws of the development of high myopia.
Investigators
Yizhi Liu
Clinical Professor,director of Zhongshan Ophthalmic Center
Zhongshan Ophthalmic Center, Sun Yat-sen University
Eligibility Criteria
Inclusion Criteria
- •9 to 18 years old school students in Guangzhou, with either eye had myopia equal or greater than 6.0D
- •Or 6 to 8 years old school students in Guangzhou, with either eye had myopia equal or greater than 3.0D
- •Written informed consent for study participation
- •Be willing to cooperate with the relevant ophthalmological examination and complete the questionnaire.
Exclusion Criteria
- •None school students in Guangzhou
- •Other contraindications
- •A history of allergy to tropicamide or topical anesthetics
- •Missing ability to give informed consent
Outcomes
Primary Outcomes
To observe the relationship between the changes of ocular structure parameters and pathological changes among children with high myopia.
Time Frame: examine every 12 months, follow up 3 years
examine the ocular pathological changes
Secondary Outcomes
- To explore the impact of environmental factors and genetic factors on the progression among children and adolescents with high myopia(examine every 12 months, follow up 3 years)