Axial Involvement in Psoriatic Arthritis LUMC

Recruiting

Conditions: psoriatic arthritis
10023213

Registration Number: NL-OMON53984

Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 20

Inclusion Criteria

1) Age >= 18 years.
2) Definite diagnosis of PsA.
3) Fulfilment of the CASPAR criteria for PsA.
4) Duration of PsA symptoms <=10 years.
5) Written informed consent.

Exclusion Criteria

1) Unable or unwilling to give informed consent or to comply with the protocol.
2) Current or past treatment with biologic or a targeted synthetic
disease-modifying antirheumatic drug (DMARDs).
3) Contraindications for MRI and/or plain radiograph examination of sacroiliac
joints and spine.

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The frequency of axial involvement in patients with psoriatic arthritis will be<br /><br>expressed as an absolute number and as a percentage based on both local and<br /><br>central assessment.<br /><br><br /><br>The burden can be considered to be very low. Information is obtained from<br /><br>patient records or the treating physician at baseline. Patients receive usual<br /><br>care and they will not receive any intervention. Since the nature of this study<br /><br>is observational, and the burden on the participants is very low, there will<br /><br>not be any risks in taking part in this study</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Frequency of active inflammatory and structural changes on imaging suggestive<br /><br>of inflammatory involvement of axial skeleton (sacroiliac joints and spine) in<br /><br>psoriatic arthritis will be expressed an absolute number and as a percentage;</p><br>