ISRCTN83738615
Completed
Not Applicable
Perioperative myocardial ischaemia and cytokine response in patients undergoing high-risk surgery: the influence of fluvastati
Erasmus Medical Centre (Netherlands)0 sites500 target enrollmentMarch 7, 2007
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Perioperative myocardial ischaemia
- Sponsor
- Erasmus Medical Centre (Netherlands)
- Enrollment
- 500
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Aged greater than 40 years
- •2\. Scheduled for elective noncardiac surgery
- •3\. Risk score for perioperative cardiovascular death greater than or equal to 51 points
- •5\. Written informed consent
Exclusion Criteria
- •1\. Currently on statin therapy
- •2\. Contraindication for statin therapy
- •3\. Scheduled for surgery which interferes with continuous 12\-lead Electrocardiogram (ECG) recording, such as thoracic and upper abdominal surgery
- •4\. Unstable coronary disease
- •5\. Undergoing emergency surgery
- •6\. Patients with extensive stress\-induced ischaemia during dobutamine stress test
- •7\. Creatine Kinase (CK) at baseline greater than 10 x Upper Limit of Normal (ULN)
- •8\. Previous participation in the fluvastatin\-study
- •9\. Reoperation within 30 days of an initial surgical procedure
- •10\. Participation in another clinical trial within the last 30 days
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Not Applicable
Perioperative myocardial ischemia and cytokine response in patients undergoing high-risk surgery; the influence of fluvastatin.statinperioperativevascular surgeryinflammationNL-OMON27929Erasmus MC, Rotterdam, the Netherlands.500
Not yet recruiting
Not Applicable
Effect of different anesthetic techniques on inflammatory markers in patients undergoing major orthopedic trauma surgeryHealth Condition 1: S723- Fracture of shaft of femurCTRI/2020/01/022682AIIMS
Unknown
Not Applicable
Clinical Impact of Cytokine in Cardiac SurgeryCoronary DiseaseNCT02213939University Hospital of Cologne300
Recruiting
Not Applicable
Removal of cytokines during cardiac surgeryPostoperative inflammatory responseOrgan failureDRKS00007928niversitätsklinikum Köln40
Completed
Not Applicable
The influence of perioperative myocardial ischemia on postoperative complications in abdominal surgical patients at risk for coronary artery disease.anginamyocardial ischemia1002859310017998NL-OMON39296Sint Antonius Ziekenhuis196