Effects of Delayed Muscle Pain on Respiratory Muscle Function

Not Applicable

Completed

• Conditions: Muscle Soreness; Exercise; Respiratory Function Tests; Respiratory Muscles
• Interventions: Other: DOMS protocol

• Registration Number: NCT05276986
• Lead Sponsor: Ankara Yildirim Beyazıt University

Brief Summary

The aim of the study was to determine whether delayed-onset muscle soreness (DOMS) in trunk muscles has an effect on respiratory function parameters, respiratory muscle strength, respiratory muscle endurance, and exercise capacity.

Detailed Description

In 24 healthy university students was induced for the trunk muscles with a load equals to 80% of the maximum repetitive voluntary contraction. Pulmonary function parameters, respiratory muscle strength and endurance, exercise capacity, pain, fatigue, and dyspnea perception severity were recorded before DOMS and at the 24th and 48th hours after DOMS.

After DOMS, there is a decrease in respiratory performance values and exercise capacity of healthy individuals and athletes. Therefore, it should be taken into account that delayed muscle soreness before the competition may affect performance. It may be beneficial to take precautions for delayed muscle pain while creating training and exercise programs, and to create treatment programs in case of the emergence of DOMS.

Study Timeline

• Study Start: 2019-11-17
• Primary Completion: 2020-01-12
• Study Completion: 2020-01-12
• Status Verified: 2022-01
• Study First Submitted: 2022-01-12
• Study First Submitted QC: 2022-03-02
• Last Update Submitted: 2022-03-02
• Study First Posted: 2022-03-14
• Last Update Posted: 2022-03-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• Being a healthy individual between the ages of 18-25
• Not having a regular exercise habit
• No infection until at least 3 weeks before the study

Exclusion Criteria

• Lung disease
• Cardiovascular disease
• Neurological disease
• Orthopedic disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
DOMS protocol group	DOMS protocol	DOMS was induced for the trunk muscles with a load equals to 80% of the maximum repetitive voluntary contraction. Pulmonary function parameters, respiratory muscle strength and endurance, exercise capacity, pain, fatigue, and dyspnea perception severity were recorded before DOMS and at the 24th and 48th hours after DOMS.

Primary Outcome Measures

Name	Time	Method
Respiratory Muscle Strength Measurement	This test was carried out at 48th hours after DOMS.	Respiratory muscle strength validity and reliability were demonstrated by measuring maximal inspiratory (MIP) and maximal expiratory (MEP) pressures with a portable intraoral pressure measuring device (MicroRPM Respiratory Muscle Testing, Germany). Measurements were made using a clamp that prevents nasal breathing and were performed 5 times until a difference of 5 cmH2O remained, with a 30-second rest period between measurements to record the best value, and the best result was recorded in cmH2O. The recorded values were calculated and recorded with the expected values according to age and gender.
Pulmonary Function Tests (FEV1)	Pulmonary function test measurements were made in all individuals at the 48th hours after the trunk-oriented DOMS.	Forced expiratory volume in the first second (FEV1) was evaluated. It is the volume of air expelled in the first second from the start of the forced vital capacity maneuver. It gives information about the restriction on major airlines in general.Test were performed using a portable spirometer (MIR Spirolab III srl, Italy). During the test, the subject was in a sitting position and their nose was clamped. The test were repeated three times and the best measurement value was used. Individuals were asked to make a forced expiration after maximum inspiration.
Pulmonary Function Tests (FVC)	Pulmonary function test measurements were made in all individuals at the 48th hours after the trunk-oriented DOMS.	Forced vital capacity (FVC) was evaluated. The volume of air that is exhaled quickly and strongly following a deep inspiration. Test were performed using a portable spirometer (MIR Spirolab III srl, Italy). During the test, the subject was in a sitting position and their nose was clamped. The test were repeated three times and the best measurement value was used.
Exercise Capacity	This test was carried out at 48th hours after DOMS.	The exercise capacity of the individuals was evaluated with the 6-Minute Walk Test (6 MWT), a submaximal test with high validity and reliability (ICC=0.94). 6MWT, made according to the American Thoracic Society guidlines.The distance covered in a 6-minute walk was calculated from the number of laps and meters. Values were recorded as a percentage of expected values for age and sex.
Respiratory Muscle Endurance Test	This test was performed at 48 hours after DOMS.	Respiratory muscle endurance was evaluated with a threshold-loaded (constant) respiratory muscle trainer (Power Breathe®, POWERbreathe International Ltd. Warwickshire, England) with proven validity and reliability . In the evaluation, measurements were made in the upright sitting position in the chair while the nose of the individuals was closed with a clip.; Initial workload was applied at 60% of the maximal inspiratory pressure. Participants were asked to continue inspiring despite constant inspiratory workload.; The respiratory muscle endurance value was obtained by multiplying the maximum workload of the test that can be sustained for at least one minute.; Individuals were told that the test could be terminated if severe fatigue and extreme shortness of breath were experienced during the test.; The results of the test were recorded.
Pulmonary Function Tests (FEF25%-75%)	Pulmonary function test measurements were made in all individuals at the 48th hours after the trunk-oriented DOMS.	Flow rate value of forced expiratory volume (FEF25%-75%) was evaluated. It is the mean flow rate in 50% of the forced vital capacity maneuver. Test were performed using a portable spirometer (MIR Spirolab III srl, Italy). During the test, the subject was in a sitting position and their nose was clamped. The test were repeated three times and the best measurement value was used. Individuals were asked to make a forced expiration after maximum inspiration.
Pulmonary Function Tests (VC)	Pulmonary function test measurements were made in all individuals at the 48th hours after the trunk-oriented DOMS.	Vital capacity (VC) was evaluated. It is the volume of air in the lungs that varies between full inspiration and maximum expiration. It is possible to measure the volume of both a slow and vigorous exhalation after a deep inspiration.Test were performed using a portable spirometer (MIR Spirolab III srl, Italy). During the test, the subject was in a sitting position and their nose was clamped. The test were repeated three times and the best measurement value was used.

Trial Locations

Locations (2)

Ankara Yildirim Beyazit University,Faculty of Health Sciences, Physiotherapy and Rehabilitation Department; 🇹🇷 Ankara, Turkey

Faculty of Health Sciences, Departmant of Physiotherapy and Rehabilitation, Baskent University; 🇹🇷 Ankara, Turkey