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Post-stroke Pathway: Analysis and Link With One Year Sequelae in a French Cohort of Stroke Patients

Conditions
Stroke Sequelae
Stroke
Registration Number
NCT03865173
Lead Sponsor
University Hospital, Bordeaux
Brief Summary

The link between post-stroke pathways and patient sequelae have not yet been clearly defined. The main purpose is to identify the post-stroke life pathways components associated with sequalae at 3 months and 1 year after the acute stroke episode.

Detailed Description

Stroke is a serious health event, involving the entire health care system and generating considerable socioeconomic weight for society. Knowledge of the components, the diversity and the scalability of post-stroke life pathways is currently not sufficient. Moreover the link between post-stroke pathways and patient sequelae have not yet been clearly defined.

The main purpose is to identify the post-stroke life pathways components associated with sequalae at 3 months and 1 year after the acute stroke episode. The secondary objectives are: 1) To define a typology of the life pathways of stroke patients, , 2) To analyze the social and geographical inequalities in the management of stroke, 4) To estimate the cost of the pathway elements of stroke management; 5) Measure the sequelae of stroke patients at three months and one year after the acute episode.

The design is a prospective multicenter cohort study with a follow up to 1 year after the acute episode, managed in several hospitals in the Aquitaine region (France).

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
1138
Inclusion Criteria
  • Patient being over 18 years of age living in metropolitan France;
  • Patient with recent stroke (not before 2019) whose diagnosis confirmed by a neuro-vascular physician;
  • Patient managed for stroke in one of the 13 participating hospitals of the Aquitaine region;
  • Patient giving consent to participate to PAPASéPA;
  • Patient to be alive at the end of the acute management hospital stay
Exclusion Criteria
  • Patient refuse to participate to PAPASéPA
  • Patient died during the initial stay

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Modified Rankin Scale (mRS) Score1 year

Activity limitations post-stroke measure Minimum score : 0 "no symptom" Maximum score : 6 "death"

Secondary Outcome Measures
NameTimeMethod
Telephone Interview for Cognitive Status Modified (TICS) Score1 year

Cognitive disorders post-stroke measure Score from 0 to 43

Hospital anxiety and depression scale (HADS) Score1 year

Depression and anxiety disorders post-stroke measure Scores ranged from 0 (minimum) to 21 (maximum) for anxiety and 0 (minimum) to 21 (maximum) for depression.

Total score from 0 to 42

Fatigue Severity Scale (FSS) Score1 year

The Fatigue Severity Scale (FSS) is designed to differentiate fatigue from clinical depression, since both share some of the same symptoms. Essentially, the FSS consists of answering a short questionaire that requires the subject to rate his or her own level of fatigue. The subject is asked to read each statem ent and circle a number from 1 to 7, depending on how appropriate they felt the statement applied to them over the preceding week. A low value indicates that the statement is not very appropriate whereas a high value indicates agreement. The scoring is done by calculating the average response to the questions (adding up all the answers and dividing by nine).

People with depression alone score about 4.5. People with fatigue average about 6.5.

Barthel Index (BI) Score1 year

Functional outcome post-stroke measure The original 10-item form of the BI consists of 10 common ADL activities including: feeding, bathing, grooming, dressing, bowel control, bladder control, toileting, chair transfer, ambulation and stair climbing. Items are rated in terms of whether individuals can perform activities independently, with some assistance, or are dependent (scored as 10, 5 or 0). Items are weighted according to the level of nursing care required.

Total score from 0 to 100

Community Integration Questionnaire (CIQ-R) Score1 year

Participation restrictions post-stroke measure Score from 0 to 35

Trial Locations

Locations (13)

CH Agen

🇫🇷

Agen, France

CH Blaye

🇫🇷

Blaye, France

CH Arcachon

🇫🇷

La Teste de Buch, France

Clinique Mutualiste Lesparre Médoc

🇫🇷

Lesparre-Médoc, France

CH Mont de Marsan - site Layné

🇫🇷

Mont de Marsan, France

CH Orthez

🇫🇷

Orthez, France

CH Oloron

🇫🇷

Oloron-Sainte-Marie, France

CH Pau

🇫🇷

Pau, France

Pôle de Santé du Villeneuvois

🇫🇷

Villeneuve sur Lot, France

CH Libourne

🇫🇷

Libourne, France

CHU Bordeaux

🇫🇷

Bordeaux, France

CH Sud Gironde - Langon

🇫🇷

Langon, France

CHIC Marmande-Tonneins

🇫🇷

Marmande, France

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