A clinical trial to study the effect of spinal morphine in reducing the requirement of locally anesthetizing drugs in labour analgesia
Recruiting
- Conditions
- Pregnancy - labour pain
- Registration Number
- CTRI/2020/03/024119
- Lead Sponsor
- AIIMS New Delhi
- Brief Summary
A double blinded RCT on the analgesic efficacy and local anesthetic sapring effect of intrathecal morphine as adjunct for labour analgesia .
Patients will be allocated to one of the two groups.
Group M- Patients who will receive intrathecal morphine 250 μg along with bupivacaine 2 mg and fentanyl 25 μg
Group F- Patients who will receive normal saline (0.25 ml) along with bupivacaine 2mg and fentanyl 25μg
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Female
- Target Recruitment
- 70
Inclusion Criteria
1.ASA I and II 2.Primi gravida/ Mutigravida, para 0 3.Uncomplicated singleton pregnancy 4.Vertex presentation 5.Active labour 6.Requesting for labour analgesia.
Exclusion Criteria
- Local or systemic infection.
- Patient not willing to participate.
- Known allergy to study drugs.
- Bleeding disorders.
- Decreased platelet counts.
- Usage of opioids/other analgesics in last 4hours.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Effect of intrathecal morphine on Local anaesthetic requirement epidurally during labour Every 30 minutes till delivery, then every 6 hours postnatal till 24 hours.
- Secondary Outcome Measures
Name Time Method Effect of intrathecal morphine on 1. Pain scores by VAS in I, II and III stages of labour
Trial Locations
- Locations (1)
All India Institute if medical sciences
🇮🇳Delhi, DELHI, India
All India Institute if medical sciences🇮🇳Delhi, DELHI, IndiaDrRushil VladimirPrincipal investigator9811461831rushilvladimir94@gmail.com