Use of a drug (norepinephrine) for prevention of fall in BP in pregnant patients posted for delivery with operation during spinal anaesthesia

Not yet recruiting

Conditions: Other complications of spinal andepidural anesthesia during labor and delivery,

Registration Number: CTRI/2022/07/044398

Lead Sponsor: RNT Medical College and MB Hospital

Brief Summary: Hypotension is the most common anaestheisa induced complication encountered in patients undergoing caesarean section under spinal anaesthesia.This study aims at evaluating the role of manually titrated infusion of norepinephrine in prevention of hypostension in parturients undergoing lower segment caesarean section under sub arachnoid block.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: Female

Target Recruitment: 140

Inclusion Criteria

American society of anaesthesiologists physical status less than 3 Nonlaboring, Normotensive, Term and singleton pregnancy taken up for elective caesarean section under spinal anaesthesia like previous caesarean section, Breech presentation, Cephalopelvic disproportion, Pregnancy following infertility treatment, Cord round neck, Non progression of labour, Baseline systolic BP 90-140 mm Hg.

Exclusion Criteria

Patient refusal, Emergency indication of caesarean section like antepartum haemorrhage, Fetal distress, Obstructed labour, Umbilical coed prolapse, Preeclampsia, Gestational diabetes, Essential hypertension, More than 2 previous lscs, History of PPH, Multiple gestation, Patients with associated systemic illness, History of seizures, Coma,neurological signs or Symptoms,any allergy to local anaesthetic agent, Weight<50kg>100kg Height <140cm>180cm.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of hypotension	Intraoperatively till delivery of baby (30min)

Secondary Outcome Measures

Name	Time	Method
Total norepinephrine consumption, Haemodynamic parameters, rescue doses of vasopressor	Intraoperatively (1hr)

Trial Locations

Locations (1): Pannadhay Zanana Hospital
🇮🇳
Udaipur, RAJASTHAN, India
Pannadhay Zanana Hospital
🇮🇳Udaipur, RAJASTHAN, India
Dr Chanchel mary thomas
Principal investigator
9884609119
chanchelmarythomas@gmail.com