Study of the effect of Nandrolone ampoule in facilitating the separation of mechanical ventilatio

Phase 3

Recruiting

Conditions: All patients have long-term ventilation with the same Apache screw.

Registration Number: IRCT20180804040695N1

Lead Sponsor: Zanjan University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 30

Inclusion Criteria

Patient with long-term separation of mechanical ventilation (over SBT 3 or 7 days from the first SBT to 3 weeks)
separate inspiration weakness (caused by myopathy or neuropathy caused by respiratory muscles for any reason).
Age 20 to 70 years
Sepsis or febrile illness that causes a kind of neuropathy.
Lack of lung disease (such as nano-pulmonary pleural effusion-respiratory failure-pulmonary mass and COPD)
Patients with the same nutrition or gavage
Length of stay in ICU less than 21 days.
No electrolyte imbalance
NIF having> 30

Exclusion Criteria

Reintubation
Patient death before ICU clearance
NPO becoming patient during examination
Incidence of pulmonary edema, ARDS, pleural effusion and ventilator pneumonia
Electrolyte disturbances (hypokalemia, etc.) at any time during the study.
Dissatisfaction with the patient's companions
Contraindication for the injection of nandrolone such as CHF, recent history of IHD or MI, obstructive europoplasty (BPH) in men, hematocrit over 50 (erythrocytosis), and chronic kidney and liver disease (Increase LFT)

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Facilitate separation of ventilators in patients with long-term mechanical ventilation. Timepoint: In 3 stages, 3, 5 and 7 per week, variables such as static capacity, R.S.R.I, I.W.I, CORP Index. Method of measurement: Questionnaire (Static Compliace, R.S.R.I, I.W.I, CORP Index).

Secondary Outcome Measures