Study to compare between Excimer and Narrow Band Ultraviolet-B (NBUVB) Following Autologous Non-Cultured Non-Trypsinized Epidermal Cellular Graft (Jodhpur Technique) in Management of Stable Vitiligo
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- To compare extent of repigmentation between patches treated with excimer lamp and NBUVB light following non-cultured non-trypsinized epidermal cellular graft (Jodhpur Technique) in management of stable vitiligo
研究概览
简要总结
Toltal number of 50 patches from stable vitiligo patients to be included in the study all of which will first undergo Autologous non-cultured non-trypsinized epidermal cellular graft (Jodhpur Technique) following which half of the pathes will be irradiated with Excimer lamp and other half will be irradiated with NBUVB light. The randomisation is done by computer generated systed. Results will be assessed in form of extent of repigmentation, colour matching with surrounding skin and side effects at the 6 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with stable vitiligo for more than 1 year who are not responding to medical treatment to be recruited.
排除标准
- •Pregnant and lactating females, patients with history of keloidal tendency, bleeding disorders.
- •If infection is present at the site of surgery.
- •Patients with unrealistic expectations, who are immunocompromised, with history of melanoma or skin cancer and non-compliant patients.
结局指标
主要结局
To compare extent of repigmentation between patches treated with excimer lamp and NBUVB light following non-cultured non-trypsinized epidermal cellular graft (Jodhpur Technique) in management of stable vitiligo
时间窗: 4, 5 and 6 months
次要结局
- To compare color matching and side effects of excimer and NBUVB following Jodhpur Technique(Till 6 months)
研究者
Pragya Choudhary
Dr S N Medical College, Jodhpur